In the Oguri laboratory, we are developing concise and flexible synthetic approaches to generate functional molecules based on the structure, biosynthesis, and biological roles of natural products as the evolutionary consequences of life. With integration of the biosynthetic logics and modern strategies of organic synthesis, biomimetic modular assembly lines were devised to gain divergent access to skeletally diverse molecules. The densely functionalized natural products and their variants have been utilized as covalent ligands to investigate chemical genetic and medicinal research relevant to infectious diseases and tumors. We are also exploring the interface of natural products and supramolecular chemistry by harnessing the largely untapped potential of natural products bearing specific molecular recognition capabilities. Our research and educational activities are aimed at nurturing the next generation leaders who create new values and explore the frontier of chemical research and industries.
受験希望者は事前に大栗 (hirokioguri[at]g.ecc.u-tokyo.ac.jp) へご連絡ください。 対面/Web面談(Zoomなど)を実施する予定です。 If you are interested in taking the exam, please contact Hiroki Oguri (hirokioguri[at]g.ecc.u-tokyo.ac.jp) in advance. Onsite or Web interviews (Zoom, etc.) will be conducted.
What's New
2024.07.23A review on chemo-enzymatic total synthesis has been published in BJOC! (Ryo Tanifuji,* Hiroki Oguri,* BJOC 2024, 20, 1693–1712.)......Read more
2024.07.11Assistant Professor Tanifuji participated in the 40th Annual Meeting of the Japan DDS Society, gave an oral presentation, and received the Journal Award (Biointerphases, AIP Publishing)!......Read more
2024.07.05Wayama-san, Kanno-san, Yabe-san, Oki-san, Yoshida-san, and Tanifuji have participated in 第57回天然物化学談話会 @ Nagoya Univ.......Read more
2024.06.25Prof. Andrei Yudin (Univ. Toronto) delivered the 1949th Zasshikai Seminar, including strategies for modifying macrocyclic structures!......Read more
2024.06.24We hosted the 24th Tateshina Conference on Organic Chemistry!......Read more
2024.06.07Prof. Paul A. Wender (Stanford Univ.) delivered lectures over four days, including the 1944th Zasshikai Seminar!......Read more
2024.05.28"Modern Natural Product Synthesis" featuring chapter 7 on the Chemo-enzymatic total synthesis of saframycin A has been Published!......Read more
2024.05.17Dr. Naoto Yamasaki (Nagoya Univ.) delivered an incredibly encouraging lecture featuring his achievements! Thank you very much!......Read more